The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene.

推荐稀释比 WB:1/500-1/1000

Western blot analysis of ARFGAP1 in 293T, PC-3, NIH/3T3 lysates using ARFGAP1 antibody

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。