The membrane protein encoded by this gene is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. The encoded protein can homodimerize or heterodimerize with other pore-forming subunits to form a potassium channel. This channel may act as a receptor for sour tastes.

Western

Western blot analysis of HCN1 in Hela lysates using HCN1 antibody.

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human thyroid cancer using HCN1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.