人CD40检测抗体 Human CD40 Detection Antibody（37106ES）

CD40 is a 48 kD typel glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154(CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-lgM, IL4or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.

短期保存2~8℃，长期保存-25~-15℃。