产品简介
SN38 is the active metabolite of the chemotherapy drug irinotecan (Camptosar). It is a topoisomerase I inhibitor, prevents the enzyme from properly resealing the DNA strands after they have been unwound, which leads to the accumulation of DNA damage.
产品性质
来源 |
Monoclonal anti-SN38 antibody, is produced from a hybridoma which was obtained from a mouse immunized with SN38.. |
缓冲液 |
1×PBS, pH7.4. |
克隆类型 |
Monoclonal Antibody |
亚型 |
IgG1 |
宿主 |
Mouse |
消光系数 |
1.4 |
浓度 |
1 mg/mL |
纯度 |
>95% as determined by reduced SDS-PAGE >99% as determined by non-reduced SDS-PAGE > 99% as determined by SEC-HPLC |
活性 |
EC50=80.5 ng/mL by ELISA |
应用 |
ELISA |
储存条件
-25~-15℃保存
注意事项
1. 避免反复冻融。
2. 本产品仅作科研用途。
3. 为了您的安全和健康,请穿实验服并佩戴一次性手套操作。
产品数据
SDS-PAGE
SEC-HPLC
ELISA Data
Ver.CN20240726