POU2F1通过PINK1/帕金森蛋白依赖的线粒体自噬机制调节线粒体稳态,从而促进高血压性心脏纤维化的发展。
POU2F1 promotes hypertensive cardiac fibrosis by regulating mitochondrial homeostasis through PINK1/Parkin‑dependent mitophagy
Yongbo Ma, Xiaozhe Chen, Zixian Liu, Yulong Ma, Chunlei Hou, Yunfeng Li, Mingtai Gui, Bo Lu, Deyu Fu, Mingzhu Wang
Journal:Molecular Medicine Reports
IF:5
DOI:10.3892/mmr.2026.14001
PMID:42663288
Published:2026-08-26
research field:线粒体生物学心脏病学线粒体自噬分子医学基因调控
Abstract
Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.
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