IGFL2-AS1-induced suppression of HIF-1α degradation promotes cell proliferation and invasion in colorectal cancer by upregulating CA9
Mengdi Qin, Qiang Liu, Wei Yang, Qiaofeng Wang, Zheng Xiang
Journal：Cancer Medicine
IF：4.71
DOI：10.1002/cam4.5562
PMID：
Published：2022-12-20
research field：肿瘤学分子生物学癌症遗传学细胞生物学
Abstract
The lncRNA IGFL2‐AS1 is a known cancer‐promoting factor in colorectal cancer (CRC); nonetheless, the mechanism of its carcinogenic effects has not yet been elucidated. This study elaborated on the role and underlying molecular mechanism of IGFL2‐AS1 in promoting CRC cell functions.
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