Chlorpheniramine maleate对组胺 H1 受体具有拮抗作用.
|
英文别名 (English Synonym) |
Chlorpheniramine Maleate |
|
中文名称 (Chinese Name) |
马来酸氯苯那敏 |
|
靶点 (Target) |
Histamine Receptor |
|
通路 (Pathway) |
Neuroscience |
|
CAS号 (CAS NO.) |
113-92-8 |
|
分子式 (Formula) |
C16H19ClN2·C4H4O4 |
|
分子量 (Molecular Weight) |
390.86 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Kelly JX, Smilkstein MJ, Cooper RA, Lane KD, Johnson RA, Janowsky A, Dodean RA, Hinrichs DJ, Winter R, Riscoe M. Design, synthesis, and evaluation of 10-N-substituted acridones as novel chemosensitizers in Plasmodium falciparum. Antimicrob Agents Chemother. 2007 Nov,51(11):4133-40. doi: 10.1128/AAC.00669-07. Epub 2007 Sep 10. PMID: 17846138, PMCID: PMC2151415.[2]Takano N, Arai I, Kurachi M. Analysis of the spontaneous scratching behavior by NC/Nga mice: a possible approach to evaluate antipruritics for subjects with atopic dermatitis. Eur J Pharmacol. 2003 Jun 27,471(3):223-8. doi: 10.1016/s0014-2999(03)01828-4. PMID: 12826242.
