Stavudine是一种口服活性核苷逆转录酶抑制剂，对HIV-1与HIV-2均具有抗病毒活性；该化合物可抑制线粒体DNA复制，降低NLRP3炎症小体活化，调节β淀粉样蛋白自噬过程，并能诱导细胞凋亡。
| 英文别名 (English Synonym) | Stavudine (d4T) |
| 中文名称 (Chinese Name) | 司他夫定 |
| 靶点 (Target) | HIV |
| 通路 (Pathway) | Microbiology/Virology |
| CAS号 (CAS NO.) | 3056-17-5 |
| 分子式 (Formula) | C10H12N2O4 |
| 分子量 (Molecular Weight) | 224.21 |
| 纯度 (Purity) | ≥98% |
| 溶解性 (Solubility) | 溶于DMSO |
-25~-15℃保存，有效期3年
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[2] Igoudjil A, Abbey-Toby A, Begriche K, Grodet A, Chataigner K, Peytavin G, Maachi M, Colin M, Robin MA, Lettéron P, Feldmann G, Pessayre D, Fromenty B. High doses of stavudine induce fat wasting and mild liver damage without impairing mitochondrial respiration in mice. Antivir Ther. 2007;12(3):389-400. PMID: 17591029.
