Eupatilin是从艾叶(Artemisia plants)中分离的亲脂性黄酮类化合物,作为PPARα激动剂,具有抗凋亡、抗氧化、抗炎、抗肿瘤、抗过敏等多种生物活性。
| 英文别名 (English Synonym) | Eupatilin |
| 中文名称 (Chinese Name) | 异泽兰黄素 |
| 靶点 (Target) | Others |
| 通路 (Pathway) | Natural Products |
| CAS号 (CAS NO.) | 22368-21-4 |
| 分子式 (Formula) | C18H16O7 |
| 分子量 (Molecular Weight) | 344.32 |
| 纯度 (Purity) | ≥98% |
| 溶解性 (Solubility) | 溶于DMSO |
-25~-15℃保存,有效期3年
[1] Jung Y, Kim JC, Park NJ, Bong SK, Lee S, Jegal H, Jin LT, Kim SM, Kim YK, Kim SN. Eupatilin, an activator of PPARα, inhibits the development of oxazolone-induced atopic dermatitis symptoms in Balb/c mice. Biochem Biophys Res Commun. 2018 Feb 5;496(2):508-514. doi: 10.1016/j.bbrc.2018.01.098. Epub 2018 Jan 17. PMID: 29353040.[2]Jung Y, Kim JC, Choi Y, Lee S, Kang KS, Kim YK, Kim SN. Eupatilin with PPARα agonistic effects inhibits TNFα-induced MMP signaling in HaCaT cells. Biochem Biophys Res Commun. 2017 Nov 4;493(1):220-226. doi: 10.1016/j.bbrc.2017.09.043. Epub 2017 Sep 9. PMID: 28899779.[3]Du L, Chen J, Xing YQ. Eupatilin prevents H2O2-induced oxidative stress and apoptosis in human retinal pigment epithelial cells. Biomed Pharmacother. 2017 Jan;85:136-140. doi: 10.1016/j.biopha.2016.11.108. Epub 2016 Dec 5. PMID: 27930977.





