五水头孢他啶（GR20263）是一种具有广谱抗菌活性的抗生素，对需氧革兰氏阳性菌、革兰氏阴性菌（包括产β-内酰胺酶的肠杆菌科细菌）均有效，且对大多数β-内酰胺酶稳定。
|
英文别名 (English Synonym) |
Ceftazidime pentahydrate |
|
中文名称 (Chinese Name) |
头孢他啶五水合物 |
|
靶点 (Target) |
Others |
|
通路 (Pathway) |
Others |
|
CAS号 (CAS NO.) |
78439-06-2 |
|
分子式 (Formula) |
C22H32N6O12S2 |
|
分子量 (Molecular Weight) |
636.65 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Kamali E, Jamali A, Izanloo A, Ardebili A. In vitro activities of cellulase and ceftazidime, alone and in combination against Pseudomonas aeruginosa biofilms. BMC Microbiol. 2021 Dec 16;21(1):347. doi: 10.1186/s12866-021-02411-y. PMID: 34915848; PMCID: PMC8675527.[2]MacVane SH, Crandon JL, Nichols WW, Nicolau DP. Unexpected in vivo activity of ceftazidime alone and in combination with avibactam against New Delhi metallo-β-lactamase-producing Enterobacteriaceae in a murine thigh infection model. Antimicrob Agents Chemother. 2014 Nov;58(11):7007-9. doi: 10.1128/AAC.02662-14. Epub 2014 Sep 15. PMID: 25223998; PMCID: PMC4249434.
