2-Methoxyestradiol，又称2-甲氧雌二醇，是17β-雌二醇(E2)的内源性代谢物，最早发现于妊娠妇女的尿液中，具有抗癌活性，是一种微管蛋白组装的抑制剂，可破坏微管，使微管解聚，进而抑制有丝分裂。

参考文献

[1] Rao PN, Cessac JW, Tinley TL, et al. Synthesis and antimitotic activity of novel 2-methoxyestradiol analogs. Steroids. 2002 Dec;67(13-14):1079-89. doi: 10.1016/s0039-128x(02)00066-1(IF:2.136).

[2] Kang SH, Cho HT, Devi S, et al. Antitumor effect of 2-methoxyestradiol in a rat orthotopic brain tumor model. Cancer Res. 2006 Dec 15;66(24):11991-7. doi: 10.1158/0008-5472.CAN-06-1320(IF:8.378).

[3] Kamath K, Okouneva T, Larson G, et al. 2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules. Mol Cancer Ther. 2006 Sep;5(9):2225-33. doi: 10.1158/1535-7163.MCT-06-0113(IF:4.856).

-25~-15℃保存，有效期3年。