_{Thiazovivin (Tzv)是一种新型有效的ROCK抑制剂，IC50为0.5 μM，对细胞增殖影响较小，但当与SB 431542和PD 0325901联用时，可大大提高成纤维细胞重编程生成诱导多能干细胞(iPSCs)的效率，提高胰蛋白酶消化后后人类胚胎干细胞(hESCs)的存活率。}

参考文献

1. Xu Y, et al. Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8129-34.
2. Hu K, et al. Efficient generation of transgene-free induced pluripotent stem cells from normal and neoplastic bone marrow and cord blood mononuclear cells. Blood. 2011 Apr 7;117(14):e109-19.
3. Park S, et al. Thiazovivin, a Rho kinase inhibitor, improves stemness maintenance of embryo-derived stem-like cells under chemically defined culture conditions in cattle. Anim Reprod Sci. 2015 Oct;161:47-57.

冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。