CXCL12, also known as SCYB12, PBSF and SDF-1 beta, is an 8.3 kDa, heparin-binding member of the CXC (or alpha-) family of chemokines. SDF-1 is highly conserved between species, mouse CXCL12β shares approximately 92 % amino acid sequence identity with human CXCL12β. In all SDF-1 isoforms, SDF-1β is the canonical sequence. It has the complete amino acids in the C-terminal tail. On the cell surface, the receptor for this chemokine is CXCR4 and syndecan4. CXCL12 is strongly chemotactic for T-lymphocytes, monocytes, but not neutrophils. Although alpha and beta isoforms show similar activity, SDF-1 alpha is differentially processed, and different cells secrete the two isoforms. SDF-1 alpha and beta are reported to be monomers at neutral pH and physiologic ionic strength.

高纯度、高活性、低内毒素、高批间一致性

-25 ~ -15℃保存，收到货之后有效期1年。 复溶后，无菌条件下，2~8℃保存，7天有效期。复溶后， 无菌条件下，-85 ~ -65℃保存，3个月有效期。