Recombinant Humanβ-NGF Protein_90473ES（90473ES）

β-NGF is the biologically active form of Nerve Growth Factor (NGF), a founding member of the neurotrophin family essential for neuronal development, survival, and function. Human β-NGF is a homodimeric protein composed of two identical 118-amino acid polypeptide chains. It is processed from a larger precursor (proNGF) through proteolytic cleavage. β-NGF represents a fundamental neurotrophic factor with broad applications spanning from basic neuroscience research to clinical therapeutics. While recombinant human β-NGF and gene therapy approaches aim to harness its neuroprotective properties for neurodegenerative diseases, the most significant industrial success has been the development of anti-NGF monoclonal antibodies for chronic pain management. The dual role of NGF—promoting neuronal survival in development while mediating pathological pain in adulthood—highlights the complexity of targeting this pathway therapeutically.

高活性、高纯度、低内毒素、高稳定性

-25 ~ -15℃保存，收到货之日起有效期1年。复溶后，在4°C下可稳定保存1周。复溶后，-20℃~ -80℃下可稳定保存3-6个月。建议分装后于-20℃或-80℃冷冻保存以延长保质期。