Interleukin-11 (IL-11) is a cytokine belonging to the IL-6 family that plays a crucial role in various physiological processes, including hematopoiesis, bone metabolism, and gastrointestinal mucosal protection. In rats, IL-11 is primarily produced by stromal cells in the bone marrow and other cell types, such as fibroblasts and endothelial cells. IL-11 exerts its biological effects by binding to the IL-11 receptor complex, which consists of IL-11Rα and gp130 subunits, leading to the activation of signaling pathways such as the JAK-STAT pathway. IL-11 has been shown to promote the growth and differentiation of hematopoietic progenitor cells, stimulate platelet production, and enhance bone formation. Additionally, IL-11 has anti-inflammatory properties and is being investigated for its potential therapeutic applications in conditions such as osteoporosis and inflammatory bowel disease.

高活性、高纯度、低内毒素、高批间一致性

-25 ~ -15℃保存，收到货之后有效期1年。复溶后， 2 ~ 8 °C保存，7 天有效期。复溶后， -85 ~ -65℃保存，3个月有效期。建议首次使用时将蛋白等分，避免重复冻融循环。