Aurora kinase A regulates liver regeneration through macrophages polarization and Wnt/β-catenin signalling
Yanze Yin, Defu Kong, Kang He, Qiang Xia
Journal:LIVER INTERNATIONAL
IF:5.83
DOI:10.1111/liv.15094
PMID:
Published:2021-10-31
research field:分子生物学细胞生物学肝病学
Abstract
Liver regeneration is a complex process regulated by a variety of cells, cytokines and biological pathways. Aurora kinase A (AURKA) is a serine/threonine kinase that plays a role in centrosome maturation and spindle formation during the cell division cycle. The purpose of this study was to further explore the mechanism of AURKA on liver regeneration and to identify new possible targets for liver regeneration.
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