Derivation of an induced pluripotent stem cell line (GWCMCi001-A) from PBMCs of a four-year-old male patient with Immunoglobulin A nephropathy
Xia Gao, Xin Liao, Jing Zhang, Jinai Lin, Mei Tan
Journal：Stem Cell Research
IF：4.5
DOI：10.1016/j.scr.2020.102123
PMID：
Published：2020-12-10
research field：分子生物学干细胞生物学肾病学
Abstract
Immunoglobulin A nephropathy (IgAN) is a common primary glomerular disease contributing to end-stage renal failure. In this study, the induced pluripotent stem cell line GWCMCi001-A from PBMCs of a 4-year-old male patient with IgAN using the episomal plasmids was established, which is an ideal in vitro model to understand the exact pathogenesis of IgAN.
