Silencing transcription factor FOXM1 represses proliferation, migration, and invasion while inducing apoptosis of liver cancer stem cells by regulating the expression of ALDH2
Lijian Chen, Meiyun Wu, Chunyi Ji, Miaoxian Yuan, Chaoyang Liu, Qiang Yin
Journal:IUBMB LIFE
IF:3.05
DOI:10.1002/iub.2166
PMID:
Published:2019-10-03
research field:肿瘤学分子生物学癌症研究细胞生物学
Abstract
This study is performed to explore the role of transcription factor FOXM1 in promoting the self‐renewal and proliferation of liver cancer stem cells (LCSCs) by regulating the expression of acetaldehyde dehydrogenase‐2 (ALDH2).
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