Targeting PID1 generates oxysterols to switch macrophage cell fates for improved antitumor immunity
Zheng Yuxiao, Wang Qi, Dong Chen, Wang Qiong, Han Mingshun, Zhao Haiqing, Wang Shuang, Chen Longlong, Zhang Xiaoli, Yang Dan, Xiao Jun, Chew Zhihuan, Xie Zhenfei, Yang Lei, Fan Jinyong, Zheng Xin, Tu Dezhen, Li Weiyun, Zheng Lingming, Hui Lijian, Huang Xiaowu, Li Jinsong, Tang Huiru, Wei Bin, Wang Hongyan
Journal：Nature Cancer
IF：28
DOI：10.1038/s43018-026-01189-0
PMID：
Published：2026-06-16
research field：肿瘤学肿瘤微环境分子生物学代谢免疫学细胞生物学肿瘤免疫治疗免疫学
Abstract
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