Emtricitabine是一种核苷类逆转录酶抑制剂，对乙型肝炎病毒亦具抑制活性，其细胞内半衰期达39小时，适用于HIV感染的相关研究。
| 英文别名 (English Synonym) | Emtricitabine |
| 中文名称 (Chinese Name) | 恩曲他滨 |
| 靶点 (Target) | Reverse Transcriptase |
| 通路 (Pathway) | Microbiology/Virology |
| CAS号 (CAS NO.) | 143491-57-0 |
| 分子式 (Formula) | C8H10FN3O3S |
| 分子量 (Molecular Weight) | 247.25 |
| 纯度 (Purity) | ≥98% |
| 溶解性 (Solubility) | 溶于DMSO |
-25~-15℃保存，有效期3年
[1] Venhoff N, Setzer B, Melkaoui K, Walker UA. Mitochondrial toxicity of tenofovir, emtricitabine and abacavir alone and in combination with additional nucleoside reverse transcriptase inhibitors. Antivir Ther. 2007;12(7):1075-85. PMID: 18018766.[2]Borroto-Esoda K, Vela JE, Myrick F, Ray AS, Miller MD. In vitro evaluation of the anti-HIV activity and metabolic interactions of tenofovir and emtricitabine. Antivir Ther. 2006;11(3):377-84. PMID: 16759055.[3]Hazen R, Lanier ER. Relative anti-HIV-1 efficacy of lamivudine and emtricitabine in vitro is dependent on cell type. J Acquir Immune Defic Syndr. 2003 Mar 1;32(3):255-8. doi: 10.1097/00126334-200303010-00003. PMID: 12626884.
