Rosiglitazone (BRL 49653, BRL49653),也称罗格列酮,是噻唑烷二酮类胰岛素增敏剂,是选择性的,具有口服活性的PPARγ激动剂,对PPARγ1、PPARγ2和PPARγ的EC50值分别为30 nM、100 nM和60 nM。Rosiglitazone与PPARγ结合,Kd约为40 nM。Rosiglitazone也是TRPC5的激活剂(EC50=30 μM)和TRPM3的抑制剂。
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[1] Shiqi Liu, Shiyuan Hua,et al.Production of sodium alginate-gelatin composite hydrogel-based 3D cultured fat with low cholesterol and high polyunsaturated fatty acids.Food Hydrocolloids,Volume 154,2024,110156,ISSN 0268-005X,https://doi.org/10.1016/j.foodhyd.2024.110156.(IF=11.0)
冰袋运输。粉末直接保存于-20℃,有效期3年。建议分装后-20℃干燥保存,避免反复冻融。
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