Naproxen sodium是一种对COX-1和COX-2均具有抑制作用的抑制剂。
|
英文别名 (English Synonym) |
Naproxen Sodium |
|
中文名称 (Chinese Name) |
萘普生钠 |
|
靶点 (Target) |
COX |
|
通路 (Pathway) |
Neuroscience |
|
CAS号 (CAS NO.) |
26159-34-2 |
|
分子式 (Formula) |
C14H13NaO3 |
|
分子量 (Molecular Weight) |
252.24 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于H2O |
-25~-15℃保存，有效期3年
[1] Mitchell JA, Akarasereenont P, Thiemermann C, Flower RJ, Vane JR. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci U S A. 1993 Dec 15,90(24):11693-7. doi: 10.1073/pnas.90.24.11693. PMID: 8265610, PMCID: PMC48050.[2]Rosa AC, Pini A, Lucarini L, Lanzi C, Veglia E, Thurmond RL, Stark H, Masini E. Prevention of bleomycin-induced lung inflammation and fibrosis in mice by naproxen and JNJ7777120 treatment. J Pharmacol Exp Ther. 2014 Nov,351(2):308-16. doi: 10.1124/jpet.114.215152. Epub 2014 Sep 2. PMID: 25185215.
