壬二酸作为一种九碳二羧酸,可通过抑制微生物细胞蛋白合成发挥对痤疮丙酸杆菌和表皮葡萄球菌的抑菌作用,并凭借其自由基清除能力抑制色素沉着。
|
英文别名 (English Synonym) |
Azelaic acid |
|
中文名称 (Chinese Name) |
壬二酸 |
|
靶点 (Target) |
Anti-infection |
|
通路 (Pathway) |
Microbiology/Virology |
|
CAS号 (CAS NO.) |
123-99-9 |
|
分子式 (Formula) |
C9H16O4 |
|
分子量 (Molecular Weight) |
188.22 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Zhang D, Luo Z, Jin Y, Chen Y, Yang T, Yang Q, Wu B, Shang Y, Liu X, Wei Y, Zhou F. Azelaic Acid Exerts Antileukemia Effects against Acute Myeloid Leukemia by Regulating the Prdxs/ROS Signaling Pathway. Oxid Med Cell Longev. 2020 Dec 23,2020:1295984. doi: 10.1155/2020/1295984. PMID: 33425206, PMCID: PMC7775164.[2]Gollnick H, Layton A. Azelaic acid 15% gel in the treatment of rosacea. Expert Opin Pharmacother. 2008 Oct,9(15):2699-706. doi: 10.1517/14656566.9.15.2699. PMID: 18803456.
