Pyrantel pamoate是一种口服有效的驱虫剂,作为nAChR激动剂可引起寄生虫痉挛性麻痹,用于研究蛔虫、钩虫、蛲虫、毛圆线虫及旋毛虫等感染。
|
英文别名 (English Synonym) |
Pyrantel Pamoate |
|
中文名称 (Chinese Name) |
双羟萘酸噻嘧啶；恩波酸噻嘧啶；抗虫灵；双羟萘酸喹嘧啶；双羟乃酸噻嘧啶 |
|
靶点 (Target) |
Anti-infection |
|
通路 (Pathway) |
Microbiology/Virology |
|
CAS号 (CAS NO.) |
22204-24-6 |
|
分子式 (Formula) |
C23H16O6·C11H14N2S |
|
分子量 (Molecular Weight) |
594.692 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Martin RJ, Clark CL, Trailovic SM, Robertson AP. Oxantel is an N-type (methyridine and nicotine) agonist not an L-type (levamisole and pyrantel) agonist: classification of cholinergic anthelmintics in Ascaris. Int J Parasitol. 2004 Aug,34(9):1083-90. doi: 10.1016/j.ijpara.2004.04.014. PMID: 15313135.[2]Tritten L, Silbereisen A, Keiser J. In vitro and in vivo efficacy of Monepantel (AAD 1566) against laboratory models of human intestinal nematode infections. PLoS Negl Trop Dis. 2011 Dec,5(12):e1457. doi: 10.1371/journal.pntd.0001457. Epub 2011 Dec 27. PMID: 22216366, PMCID: PMC3246443.
