1-Docosanol (Behenyl alcohol)是一种饱和脂肪醇,被报道可抑制包括单纯疱疹病毒 (HSV) 在内的脂质包膜病毒。
|
英文别名 (English Synonym) |
1-Docosanol |
|
中文名称 (Chinese Name) |
1-二十二醇 |
|
靶点 (Target) |
Others |
|
通路 (Pathway) |
Others |
|
CAS号 (CAS NO.) |
661-19-8 |
|
分子式 (Formula) |
C22H46O |
|
分子量 (Molecular Weight) |
326.6 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于EtOH |
-25~-15℃保存，有效期3年
[1] Katz DH, Marcelletti JF, Khalil MH, Pope LE, Katz LR. Antiviral activity of 1-docosanol, an inhibitor of lipid-enveloped viruses including herpes simplex. Proc Natl Acad Sci U S A. 1991 Dec 1,88(23):10825-9. doi: 10.1073/pnas.88.23.10825. PMID: 1660151, PMCID: PMC53024.[2]Iglesias G, Hlywka J, Berg JE, Khalil MH, Pope LE, Tamarkin D. The toxicity of behenyl alcohol. I. Genotoxicity and subchronic toxicity in rats and dogs. Regul Toxicol Pharmacol. 2002 Aug,36(1):69-79. doi: 10.1006/rtph.2002.1565. PMID: 12383719.
