Squalene (Super Squalene) 作为胆固醇生物合成的重要中间体，具有调节血脂、保护肝脏、抗动脉粥样硬化、心脏保护、抗氧化及抑制肿瘤生长等多重药理活性。
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英文别名 (English Synonym) |
Squalene |
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中文名称 (Chinese Name) |
角鲨烯 |
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靶点 (Target) |
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通路 (Pathway) |
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CAS号 (CAS NO.) |
111-02-4 |
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分子式 (Formula) |
C30H50 |
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分子量 (Molecular Weight) |
410.72 |
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纯度 (Purity) |
≥98% |
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溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Warleta F, Campos M, Allouche Y, Sánchez-Quesada C, Ruiz-Mora J, Beltrán G, Gaforio JJ. Squalene protects against oxidative DNA damage in MCF10A human mammary epithelial cells but not in MCF7 and MDA-MB-231 human breast cancer cells. Food Chem Toxicol. 2010 Apr;48(4):1092-100. doi: 10.1016/j.fct.2010.01.031. Epub 2010 Feb 4. PMID: 20138105. [2] Gabás-Rivera C, Barranquero C, Martínez-Beamonte R, Navarro MA, Surra JC, Osada J. Dietary squalene increases high density lipoprotein-cholesterol and paraoxonase 1 and decreases oxidative stress in mice. PLoS One. 2014 Aug 12;9(8):e104224. doi: 10.1371/journal.pone.0104224. PMID: 25117703; PMCID: PMC4130590.
