Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176, FR901228, NSC630176, FK-228)，又称罗米地辛或罗咪酯肽，是HDAC选择性抑制剂，抑制HDAC1和HDAC2的活性，IC₅₀值为36 nM和47 nM，临床上可用于治疗皮肤T细胞淋巴瘤和外周T细胞淋巴瘤。

参考文献

[1] Furumai R, et al. FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases. Cancer Res. 2002 Sep 1;62(17):4916-21..

[2] Sun WJ, et al. Romidepsin induces G2/M phase arrest via Erk/cdc25C/cdc2/cyclinB pathway and apoptosis induction through JNK/c-Jun/caspase3 pathway in hepatocellular carcinoma cells. Biochem Pharmacol. 2017 Mar 1;127:90-100.

冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。