The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of this gene cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.

推荐稀释比 WB: 1/500-1/2500; FC: 1/200-1/2000

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Flow cytometric analysis of Argininosuccinate synthase 1 expression in HepG2 cells using Argininosuccinate synthase 1 antibody . Green, isotype control; red, Argininosuccinate synthase 1.

Western blotting analysis using argininosuccinate synthase 1 antibody . Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with argininosuccinate synthase 1 antibody and HRP-conjugated goat anti-mouse secondary antibody respectively. Image was developed using NaQ™ ECL Substrate Kit .

Western blotting analysis using argininosuccinate synthase 1 antibody . Argininosuccinate synthase 1 expression in wild-type (WT) and argininosuccinate synthase 1 (ASS1) shRNA knockdown (KD) HeLa cells with 20 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with argininosuccinate synthase 1 antibody and HRP-conjugated goat anti-mouse secondary antibody respectively. Image was developed using FeQ™ ECL Substrate Kit .

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