Phentolamine mesylate (Phentolamine methanesulfonate)，又称甲磺酸酚妥拉明或瑞支亭，是具有口服活性的α-肾上腺素能受体(α-adrenergic receptor)拮抗剂，对α1与α2受体均有作用，具有血管扩张活性，临床上可用于外周血管痉挛性疾病。

参考文献

[1] Gould L, et, al. Phentolamine. Am Heart J. 1976 Sep;92(3):397-402.

[2] Pan L, et, al. Phentolamine inhibits angiogenesis in vitro: Suppression of proliferation migration and differentiation of human endothelial cells. Clin Hemorheol Microcirc. 2017;65(1):31-41.

[3] Traish A, et al. Phentolamine mesylate relaxes penile corpus cavernosum tissue by adrenergic and non-adrenergic mechanisms. Int J Impot Res. 1998 Dec;10(4):215-23.

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