The CDK4/6 inhibitor dalpiciclib augments the antitumor efficacy of enzalutamide in preclinical models of castration-resistant prostate cancer through inhibition of MCM4-mediated DNA replication
Liu Yue, Ke Yuan, Yu Jingtian, Chai Mengting, Zheng Linhui, Yang Chunqian, Liu Dong, Cheng Shiyu, Xiong Zhiyuan, Feng Jialiang, Zhao Zhenpeng, Wu Chaoyan, Yu Haijun
Journal：Cell Death & Disease
IF：9.6
DOI：10.1038/s41419-026-08959-9
PMID：
Published：2026-06-05
research field：肿瘤学分子生物学泌尿肿瘤学癌症药理学
Abstract
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