Chicanine是兴山五味子中的木酚素类化合物，通过IκBα/ MAPK / ERK信号通路下调LPS诱导的RAW 264.7细胞中的促炎性细胞因子（NO、TNF-α、IL-1 β、iNOS等），发挥其抗炎活性。Chicanine具有抗肿瘤活性，应用于医药领域。

参考文献

[1]. Anti-inflammatory effects of chicanine on murine macrophage by down-regulating LPS-induced inflammatory cytokines in IκBα±/MAPK/ERK signaling pathwaysEur J Pharmacol. 2014 Feb 5; 724:168-74. 

[2]. Kenichi, et al. ChemInform Abstract: Asymmetric Synthesis of (-)-Chicanine Using a Highly Regioselective Intramolecular Mitsunobu Reaction and Revision of Its Absolute Configuration[J]. ChemInform, 2011, 42(38):no-no.

冰袋运输。粉末直接保存于-20℃，有效期2年。建议分装后-20℃干燥保存，避免反复冻融。