Abemaciclib methanesulfonate，又称甲磺酸阿贝西尼，是CDK4/6抑制剂，IC₅₀为2 nM/10 nM，具有潜在的抗肿瘤活性。

参考文献

[1] Ku BM, Yi SY, Yi SY, et al. The CDK4/6 inhibitor LY2835219 has potent activity in combination with mTOR inhibitor in head and neck squamous cell carcinoma. Oncotarget. 2016 Mar 22;7(12):14803-13. doi: 10.18632/oncotarget.7543(IF:5.168).

[2] Yadav V, Burke TF, Huber L, et al. The CDK4/6 inhibitor LY2835219 overcomes vemurafenib resistance resulting from MAPK reactivation and cyclin D1 upregulation. Mol Cancer Ther. 2014 Oct;13(10):2253-63. doi: 10.1158/1535-7163.MCT-14-0257(IF:4.856).

-25~-15℃保存，有效期3年。