Recombinant Human CD160 (His-Avi Tag)（93585ES）

CD160 (also Natural killer cell receptor BY55) is a 27-30 kDa member of the Ig superfamily. In human, it is expressed principally on nonmyeloid hematopoietic cells. These include CD56DIMCD16+ cytolytic NK cells, CD8+CD28- T cells, CD8+CD101+ IELs, NKT cells, gamma δ TCR T cells, activated CD4+ T cells, and vascular endothelial cells. CD160 was initially identified as a GPI‑linked glycoprotein. It is synthesized as a preproprotein that is 181 amino acids (aa) in length. The precursor contains a 26 aa signal sequence, a 133 aa mature molecule that shows one 96 aa V-type Ig-like domain (aa 27-122), and a 22 aa prosegment that is cleaved to generate a GPI-linkage at Ser159. GPI-linked CD160 is known to be cleaved by phospholipases and these generate an 80 kDa (presumably trimeric) band in SDS-PAGE. Alternative splice forms for CD160 are reported to exist on activated NK cells. The principal variant is an extended type I transmembrane (TM) protein that shows a 55 aa substitution for the C-terminal two amino acids. It contains a 23 aa TM segment (aa 160-182) and a 52 aa cytoplasmic region. Two other variants show deletions of the Ig-like domain in both the GPI-linked and TM form .

高纯度、高活性、低内毒素、高批间一致性

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-25 ~ -15℃保存，收到货之后有效期1年。 复溶后， 无菌条件下，-85 ~ -65℃保存，3个月有效期。