AS605240 (AS-605240)是可口服的、细胞渗透性PI3Kγ选择性抑制剂，IC₅₀为8 nM，作用于PI3Kα/β/δ的IC₅₀分别为60、270和300 nM。

参考文献

[1] Camps M, et al. Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis. Nat Med. 2005 Sep;11(9):936-43.

[2] Kobayashi N, et al. Blockade of class IB phosphoinositide-3 kinase ameliorates obesity-induced inflammation and insulin resistance. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5753-8.

冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。