Sodium 4-aminosalicylate dihydrate (4-Aminosalicylic acid sodium salt dihydrate),又称对氨基水杨酸钠二水化合物,是常用的抗结核病药,通过抑制NF-κB和清除自由基起作用,临床上主要用于治疗结核分支杆菌所致的肺结核病。
参考文献
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[2] Zheng J, et al. para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis. J Biol Chem. 2013 Aug 9;288(32):23447-56.
[3] Sy SK, et al. N-acetyltransferase genotypes and the pharmacokinetics and tolerability of para-aminosalicylic acid in drug-resistant pulmonary tuberculosis patients. Antimicrob Agents Chemother. 2015 Jul;59(7):4129-38.
冰袋运输。粉末直接保存于-20℃,有效期3年。建议分装后-20℃干燥保存,避免反复冻融。