Gambogic Acid (Beta-Guttiferrin, Guttatic Acid, Guttic Acid)，又称藤黄酸，是来自Garcinia hanburyi树的藤黄树脂，是具有细胞通透性的Caspases激活剂，EC₅₀为0.78-1.64 μM，竞争性结合Bcl-2家族的BH3结合位点，诱导多种癌细胞凋亡，具有抗癌活性。

参考文献

1.Zhai D, et al. Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins. Mol Cancer Ther. 2008 Jun;7(6):1639-46.

2.Yi T, et al. Gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing vascular endothelial growth factor receptor 2 signaling. Cancer Res. 2008 Mar 15;68(6):1843-50.

3.Wang LH, et al. Gambogic acid synergistically potentiates cisplatin-induced apoptosis in non-small-cell lung cancer through suppressing NF-κB and MAPK/HO-1 signalling. Br J Cancer. 2014 Jan 21;110(2):341-52.

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