Bikinin (Abrasin, N-(5-Bromopyridin-2-yl)succinamic acid)是一种有效的、ATP竞争性的GSK-3抑制剂，也是油菜素类固醇（BR）信号通路的强效激活剂。Bikinin也可以抑制拟南芥GSK-3、SHAGGY相关激酶和GSK-3样激酶BIN2。

参考文献

[1]. De Rybel B, et al. Chemical inhibition of a subset of Arabidopsis thaliana GSK3-like kinases activates brassinosteroid signaling. Chem Biol. 2009 Jun 26;16(6):594-604.

[2]. Min HJ, Cui LH, et al. OsBZR1 turnover mediated by OsSK22-regulated U-box E3 ligase OsPUB24 in rice BR response. Plant J. 2019 Aug;99(3):426-438.  

[3]. Rozhon W, et al. Bikinin-like inhibitors targeting GSK3/Shaggy-like kinases: characterisation of novel compounds and elucidation of their catabolism in planta. BMC Plant Biol. 2014 Jun 19; 14:172.

冰袋运输。粉末直接保存于-20℃，有效期2年。建议分装后-20℃避光保存，避免反复冻融。