Amitifadine hydrochloride是一种三重复摄取抑制剂，对5-羟色胺、去甲肾上腺素和多巴胺转运体均具有纳摩尔级的抑制活性，在HEK 293细胞中测得的IC50值分别为12nM、23nM和96nM。

/

2~8℃避光保存，有效期3年。

[1] Skolnick P, Popik P, Janowsky A, Beer B, Lippa AS. Antidepressant-like actions of DOV 21,947: a "triple" reuptake inhibitor. Eur J Pharmacol. 2003 Feb 14;461(2-3):99-104. doi: 10.1016/s0014-2999(03)01310-4. PMID: 12586204.

[2]Levin ED, Wells C, Johnson JE, Rezvani AH, Bymaster FP, Rose JE. Amitifadine, a triple monoamine re-uptake inhibitor, reduces nicotine self-administration in female rats. Eur J Pharmacol. 2015 Oct 5;764:30-37. doi: 10.1016/j.ejphar.2015.06.041. Epub 2015 Jun 20. PMID: 26101069; PMCID: PMC4941618.