IL-11 (Interleukin-11) is a cytokine that belongs to the interleukin family. It is primarily secreted by fibroblasts, macrophages, and certain types of lymphocytes. IL-11 plays an important role in various physiological and pathological processes, particularly in immune responses, inflammatory reactions, and tissue repair and regeneration.

IL-11 can influence the function of lymphocytes, promoting the proliferation and activation of certain immune cells. It is involved in both acute and chronic inflammatory processes and may contribute to the maintenance of pathological inflammation. After injury and surgery, IL-11 helps promote the proliferation of fibroblasts and collagen synthesis, facilitating tissue healing. IL-11 may have detrimental effects in certain diseases; for instance, in fibrosis, rheumatoid arthritis, and some cancers, its overexpression could lead to pathological conditions.

Due to the role of IL-11 in various diseases, researchers are exploring therapeutic strategies targeting IL-11 to develop new drugs, particularly for the treatment of fibrosis and certain types of cancer.

高纯度、高活性、低内毒素、高批间一致性

SDS-PAGE

Figure 1. On SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Bioactivity-ELISA

Figure 2.  Biotinylated Human IL-11 Protein; His-Avi Flag Tag was immobilized at 1 μg/ml (100 μL/well) on streptavidin precoated. Increasing concentrations of Anti-IL-11 hIgG4 Antibody were added.

-85 ~ -65℃保存，收到货之日起，6个月有效期。避免反复冻融，建议等分分装为一次实验使用量，分装后，-80℃冻存。