Nectin-4 is a cell adhesion protein, also known as PVRL4 (Poliovirus ReceptorLike 4). Nectin-4 is widely expressed in the human body, particularly in epithelial tissues and neural tissues. Under normal physiological conditions, Nectin-4 plays a crucial role in cell-cell adhesion and intercellular signal transduction. Additionally, research indicates that Nectin-4 also plays a key role in embryonic development and neural system development.In cancer research, Nectin-4 has been found to be associated with the development and metastasis of various cancers. High levels of Nectin-4 expression are linked to the malignancy and prognosis of certain cancers, making it a potential tumor marker. Furthermore, due to its overexpression in cancer cells, Nectin-4 is considered a potential therapeutic target, with treatment strategies targeting Nectin-4 currently under investigation.

高纯度、高活性、低内毒素、高批间一致性

SDS-PAGE

Figure 1.On SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Bioactivity-ELISA

Figure 2. Cynomolgus Nectin-4 Protein; His Tag was immobilized at 1 μg/ml (100 μL/well). Increasing concentrations of Anti-HumanNectin4 hIgG1 Antibody were added.

-85 ~ -65℃保存，收到货之日起，6个月有效期。避免反复冻融，建议等分分装为一次实验使用量，分装后，-80℃冻存。