XRCC4 (7C10) Mouse mAb
产品介绍
Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
产品性质
产品特色
推荐稀释比 WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
应用案例
Immunohistochemistry
Immunohistochemistry analysis of paraffin-embedded XRCC4 in Human lung cancer using XRCC4 (7C10) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Western
Western blot analysis of XRCC4 (7C10) in XRCC4 in T47D, 3T3, COS7, C6 and Hela lysates using XRCC4 (7C10) antibody
Immunoprecipitation
Immunoprecipitation analysis of XRCC4 in Hela lysates using XRCC4 antibody.
存储条件
-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。
COA
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