Phenformin hydrochloride盐酸苯乙福明 AMPK激活剂|CAS 834-28-6（53718ES）

Phenformin hydrochloride (NSC-756501 HCl, Phenformin HCl, Phenethylbiguanide HCl)，又称盐酸苯乙福明，是一种双胍类衍生物，用作降血糖药，具有抗糖尿病活性，通过提高AMPK磷酸化激活AMPK活性。

参考文献

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2.Zhang L, et al. Metformin and phenformin activate AMP-activated protein kinase in the heart by increasing cytosolic AMP concentration. Am J Physiol Heart Circ Physiol. 2007 Jul;293(1):H457-66.

3.Moreira AL, et al. Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation. J Exp Med. 1993 Jun 1;177(6):1675-80.

4.Woollhead AM, et al. Phenformin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR) activation of AMP-activated protein kinase inhibits transepithelial Na+ transport across H441 lung cells. J Physiol. 2005 Aug 1;566(Pt 3):781-92.

冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。