Niclosamide olamine (Niclosamide ethanolamine salt),又称氯硝柳胺乙醇胺盐或杀螺胺乙醇胺盐,是一种驱虫剂,可破坏寄生虫和动物模型中的线粒体代谢。Niclosamide olamine可逆地抑制雷帕霉素复合物(mTORC1)的哺乳动物靶标,从而抑制STAT3 (IC50: 0.25 μM)并刺激自噬反应。
参考文献
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冰袋运输。粉末直接保存于-25~-15℃,有效期2年。建议干燥避光保存,避免反复冻融。