Anti-CXCR4/CD184 Reference Antibody (ulocuplumab)
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Ulocuplumab (Anti-Human CXCR4 Recombinant Antibody/BMS-936564/MDX1338) 是一种完全人 IgG4 抗 CXCR4 抗体。Ulocplumab 诱导癌细胞凋亡 (apoptosis),能够抑制 CXCL12 介导的慢性淋巴细胞白血病 (CLL) 细胞在 CXCR4 激活下的迁移。Ulocplumab 在急性髓系白血病 (AML),非霍奇金淋巴瘤 (NHL) 和多发性骨髓瘤移植模型中显示抗肿瘤活性。
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For Powder, reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.
应用案例

本产品仅用作科学研究!


Anti-CXCR4 / CD184 Reference Antibody (ulocuplumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.

The purity of Anti-CXCR4 / CD184 Reference Antibody (ulocuplumab) is 99.48%, determined by SEC-HPLC.

Human CXCR4 Romas cells were stained with Anti-CXCR4 / CD184 Reference Antibody (ulocuplumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=5.915 nM.

存储条件
-80°C for 2 years under sterile conditions;-20°C for 1 year under sterile conditions;Avoid repeated freeze-thaw cycles.
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