BI-882370是一种高效、选择性的RAF激酶抑制剂，通过结合BRAF激酶的DFG-out无活性构象（ATP结合位点）发挥作用，对BRAFV600E突变体、野生型BRAF和CRAF的IC50值分别为0.4nM、0.8nM和0.6nM，并可抑制SRC家族激酶。

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-25~-15℃避光保存，有效期3年。

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