The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic transmembrane domains. Tetraspanins mediate signal transduction events that play a role in the regulation of immune responses, cell development, activation, growth and motility. CD37 expression is restricted to cells of the immune system, with highest abundance on mature B cells, and lower expression is found on T cells and myeloid cells. CD37 is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternate splicing results in multiple transcript variants encoding different isoforms.CD37 controls both humoral and cellular immune responses.

推荐稀释比 FC:1/50-1/100

Flow Cytometry analysis of PBMC stained with CD37 antibody(Red).Blue line histogram represents nonspecific negative control

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。