hormone sensitive lipase is a lipolytic enzyme of the 'GDXG' family. Plays a rate limiting step in triglyceride lipolysis. In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production.

Western

Western blot analysis of Phospho-HSL (S853) in (1) mouse muscle lysates; (2) mouse muscle lysates treated with AP using Phospho-Hormone Sensitive Lipase (Ser853) antibody.