Ponatinib hydrochloride(AP24534 hydrochloride)是ponatinib的盐酸盐形式，作为一种口服有效的多靶点激酶抑制剂，它能强效抑制Abl、PDGFRα、VEGFR2、FGFR1和Src等多个关键激酶靶点。

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2~8℃避光保存，有效期3年。

[1] Gover-Proaktor A, Granot G, Shapira S, Raz O, Pasvolsky O, Nagler A, Lev DL, Inbal A, Lubin I, Raanani P, Leader A. Ponatinib reduces viability, migration, and functionality of human endothelial cells. Leuk Lymphoma. 2017 Jun;58(6):1455-1467. doi: 10.1080/10428194.2016.1239258. Epub 2016 Oct 12. PMID: 27733071.

[2]Hong YP, Chen C, Guo WY, Zhao L, Mei FC, Xiang MW, Wang WX. Effects of Castanospermine on Inflammatory Response in a Rat Model of Experimental Severe Acute Pancreatitis. Arch Med Res. 2016 Aug;47(6):436-445. doi: 10.1016/j.arcmed.2016.11.007. PMID: 27986123.