厄多司坦通过抑制脂多糖（LPS）诱导的NF-κB信号通路激活，发挥粘液调节、抗菌、抗炎和抗氧化等多重药理作用。
|
英文别名 (English Synonym) |
Erdosteine |
|
中文名称 (Chinese Name) |
厄多司坦 |
|
靶点 (Target) |
Others |
|
通路 (Pathway) |
Others |
|
CAS号 (CAS NO.) |
84611-23-4 |
|
分子式 (Formula) |
C8H11NO4S2 |
|
分子量 (Molecular Weight) |
249.31 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Park JS, Park MY, Cho YJ, Lee JH, Yoo CG, Lee CT, Lee SM. Anti-inflammatory Effect of Erdosteine in Lipopolysaccharide-Stimulated RAW 264.7 Cells. Inflammation. 2016 Aug;39(4):1573-81. doi: 10.1007/s10753-016-0393-4. PMID: 27317418.[2]Oktar S, Gökçe A, Aydin M, Davarci M, Meydan S, Oztürk OH, Koç A. Beneficial effect of erdosteine on methotrexate-induced testicular toxicity in mice. Toxicol Ind Health. 2010 Aug;26(7):433-8. doi: 10.1177/0748233710369666. Epub 2010 May 26. PMID: 20504824.
