分子生物学
IVD分子诊断
细胞培养与分析
蛋白研究
细胞因子
重组蛋白
抗体
高通量测序建库
病原检测UCF系列
生物医药
工具酶
抑制剂激活剂与常用试剂
仪器
耗材
Recombinant Mouse IL-21R Protein,His Tag
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产品介绍
IL-21 and IL-21R were highly expressed in the lesional skin and peripheral blood of psoriasis patients. IL-21 promoted CD4 T cells proliferation and Th17 cells differentiation and inhibiting Treg cells differentiation by upregulating RORγt expression and downregulating Foxp3 expression, with increased expression and secretion of IL-17A and IL-22.Microbial translocation and the associated immune activation during HIV-1 infection may lead to high expression levels of the IL-21R activation marker in RM B cells, a feature associated with increased apoptosis and a reduced number of these cells in the circulation.
产品性质
产品特色
高活性、高纯度、低内毒素、高稳定性
应用案例
ELISA Data: Immobilized Mouse IL-21R, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Mouse IL-21, His Avi Tag with the EC50 of 4.1ng/ml determined by ELISA.
存储条件
-25~-15℃保存,收到货之日起,有效期1年。复溶后, -85~-65℃保存,3个月有效期。避免反复冻融。
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